Ontology highlight
ABSTRACT:
SUBMITTER: Rouse SL
PROVIDER: S-EPMC4306293 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
The journal of physical chemistry. B 20141021 3
Structural studies of membrane proteins have highlighted the likely influence of membrane mimetic environments (i.e., lipid bilayers versus detergent micelles) on the conformation and dynamics of small α-helical membrane proteins. We have used molecular dynamics simulations to compare the conformational dynamics of BM2 (a small α-helical protein from the membrane of influenza B) in a model phospholipid bilayer environment with its behavior in protein-detergent complexes with either the zwitterio ...[more]