MitoBlue: a nontoxic and photostable blue-emitting dye that selectively labels functional mitochondria.

ABSTRACT: We report the discovery of a fluorogenic dye, N(1),N(3)-di(2-aminidonaphthalen-6-yl) propane-1,3-diamine, MitoBlue, which selectively stains functional mitochondria while displaying low toxicity, bright blue emission, and high resistance to photobleaching. Additionally, we show that a biotin-labeled MitoBlue derivative can be used as a handle for the delivery of streptavidin-tagged species to the mitochondria.

SUBMITTER: Sanchez MI 

PROVIDER: S-EPMC4306598 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature