Dataset Information

Trends and outcomes for donor oocyte cycles in the United States, 2000-2010.

ABSTRACT: The prevalence of oocyte donation for in vitro fertilization (IVF) has increased in the United States, but little information is available regarding maternal or infant outcomes to improve counseling and clinical decision making.To quantify trends in donor oocyte cycles in the United States and to determine predictors of a good perinatal outcome among IVF cycles using fresh (noncryopreserved) embryos derived from donor oocytes.Analysis of data from the Centers for Disease Control and Prevention's National ART Surveillance System, to which fertility centers are mandated to report and which includes data on more than 95% of all IVF cycles performed in the United States. Data from 2000 to 2010 described trends. Data from 2010 determined predictors.Good perinatal outcome, defined as a singleton live-born infant delivered at 37 weeks or later and weighing 2500 g or more.From 2000 to 2010, data from 443 clinics (93% of all US fertility centers) were included. The annual number of donor oocyte cycles significantly increased, from 10,801 to 18,306. Among all donor oocyte cycles, an increasing trend was observed from 2000 to 2010 in the proportion of cycles using frozen (vs fresh) embryos (26.7% [95% CI, 25.8%-27.5%] to 40.3% [95% CI, 39.6%-41.1%]) and elective single-embryo transfers (vs transfer of multiple embryos) (0.8% [95% CI, 0.7%-1.0%] to 14.5% [95% CI, 14.0%-15.1%]). Good perinatal outcomes increased from 18.5% (95% CI, 17.7%-19.3%) to 24.4% (95% CI, 23.8%-25.1%) (P?

SUBMITTER: Kawwass JF

PROVIDER: S-EPMC4307377 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature

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Trends and outcomes for donor oocyte cycles in the United States, 2000-2010.

Kawwass Jennifer F JF Monsour Michael M Crawford Sara S Kissin Dmitry M DM Session Donna R DR Kulkarni Aniket D AD Jamieson Denise J DJ

JAMA 20131201 22

<h4>Importance</h4>The prevalence of oocyte donation for in vitro fertilization (IVF) has increased in the United States, but little information is available regarding maternal or infant outcomes to improve counseling and clinical decision making.<h4>Objectives</h4>To quantify trends in donor oocyte cycles in the United States and to determine predictors of a good perinatal outcome among IVF cycles using fresh (noncryopreserved) embryos derived from donor oocytes.<h4>Design, setting, and partici ...[more]

PMID: 24135860

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Dataset Information

Trends and outcomes for donor oocyte cycles in the United States, 2000-2010.

Publications

Trends and outcomes for donor oocyte cycles in the United States, 2000-2010.

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