Ontology highlight
ABSTRACT:
SUBMITTER: Tinoco JC
PROVIDER: S-EPMC4308865 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Tinoco Juan Carlos JC Juergens Christine C Ruiz Palacios Guillermo M GM Vazquez-Narvaez Jorge J Enkerlin-Pauwells Hermann Leo HL Sundaraiyer Vani V Pathirana Sudam S Kalinina Elena E Gruber William C WC Scott Daniel A DA Schmoele-Thoma Beate B
Clinical and vaccine immunology : CVI 20141210 2
This open-label multicenter clinical trial conducted in Mexico assessed the immunogenicity and safety of a 13-valent pneumococcal conjugate vaccine (PCV13) in adults ≥ 50 years of age not previously vaccinated with the 23-valent pneumococcal polysaccharide vaccine (PPSV23). The PCV13 elicited a robust immune response in this study population, as reflected by the magnitude of fold rises in functional antibody levels measured by serotype-specific opsonophagocytic activity (OPA) assays before and 1 ...[more]