Cross-species sequence comparisons: a review of methods and available resources.
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ABSTRACT:
SUBMITTER: Frazer KA
PROVIDER: S-EPMC430969 | biostudies-literature | 2003 Jan
REPOSITORIES: biostudies-literature
Publications
Cross-species sequence comparisons: a review of methods and available resources.
Frazer Kelly A KA Elnitski Laura L Church Deanna M DM Dubchak Inna I Hardison Ross C RC
Genome research 20030101 1
With the availability of whole-genome sequences for an increasing number of species, we are now faced with the challenge of decoding the information contained within these DNA sequences. Comparative analysis of DNA sequences from multiple species at varying evolutionary distances is a powerful approach for identifying coding and functional noncoding sequences, as well as sequences that are unique for a given organism. In this review, we outline the strategy for choosing DNA sequences from differ ...[more]
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