Ontology highlight
ABSTRACT:
SUBMITTER: Kim C
PROVIDER: S-EPMC4311754 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Kim Choong C Kasuya Junichi J Jeon Jessie J Chung Seok S Kamm Roger D RD
Lab on a chip 20150101 1
Anti-angiogenic therapy, which suppresses tumor growth by disrupting oxygen and nutrient supply from blood to the tumor, is now widely accepted as a treatment for cancer. To investigate the mechanisms of action of these anti-angiogenesis drugs, new three dimensional (3D) cell culture-based drug screening models are increasingly employed. However, there is no in vitro high-throughput screening (HTS) angiogenesis assay that can provide uniform culture conditions for the quantitative assessment of ...[more]