Optogenetic inactivation modifies monkey visuomotor behavior.
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ABSTRACT:
SUBMITTER: Cavanaugh J
PROVIDER: S-EPMC4311889 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Publications
Optogenetic inactivation modifies monkey visuomotor behavior.
Cavanaugh James J Monosov Ilya E IE McAlonan Kerry K Berman Rebecca R Smith Mitchell K MK Cao Vania V Wang Kuan H KH Boyden Edward S ES Wurtz Robert H RH
Neuron 20121201 5
A critical technique for understanding how neuronal activity contributes to behavior is determining whether perturbing it changes behavior. The advent of optogenetic techniques allows the immediately reversible alteration of neuronal activity in contrast to chemical approaches lasting minutes to hours. Modification of behavior using optogenetics has had substantial success in rodents but has not been as successful in monkeys. Here, we show how optogenetic inactivation of superior colliculus neur ...[more]
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