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Characterization of a novel thermostable nuclease homolog (NucM) in a highly divergent Staphylococcus aureus clade.


ABSTRACT: A thermostable nuclease homologue (NucM) in an animal-associated divergent clade of Staphylococcus aureus in sub-Saharan Africa has a highly divergent nucleotide sequence compared to those of the classical nuc1 and nuc2 genes of S. aureus. Its deduced amino acid sequences, tertiary structures, and nuclease activities, however, are similar.

SUBMITTER: Schaumburg F 

PROVIDER: S-EPMC4313246 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature

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Characterization of a novel thermostable nuclease homolog (NucM) in a highly divergent Staphylococcus aureus clade.

Schaumburg Frieder F   Pauly Maude M   Schubert Grit G   Shittu Adebayo A   Tong Steven S   Leendertz Fabian F   Peters Georg G   Becker Karsten K  

Journal of clinical microbiology 20140820 11


A thermostable nuclease homologue (NucM) in an animal-associated divergent clade of Staphylococcus aureus in sub-Saharan Africa has a highly divergent nucleotide sequence compared to those of the classical nuc1 and nuc2 genes of S. aureus. Its deduced amino acid sequences, tertiary structures, and nuclease activities, however, are similar. ...[more]

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