Ontology highlight
ABSTRACT:
SUBMITTER: Merino MM
PROVIDER: S-EPMC4313366 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Cell 20150115 3
Viable yet damaged cells can accumulate during development and aging. Although eliminating those cells may benefit organ function, identification of this less fit cell population remains challenging. Previously, we identified a molecular mechanism, based on "fitness fingerprints" displayed on cell membranes, which allows direct fitness comparison among cells in Drosophila. Here, we study the physiological consequences of efficient cell selection for the whole organism. We find that fitness-based ...[more]