The value of monitoring to control evolving populations.
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ABSTRACT:
SUBMITTER: Fischer A
PROVIDER: S-EPMC4313848 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Publications
The value of monitoring to control evolving populations.
Fischer Andrej A Vázquez-García Ignacio I Mustonen Ville V
Proceedings of the National Academy of Sciences of the United States of America 20150113 4
Populations can evolve to adapt to external changes. The capacity to evolve and adapt makes successful treatment of infectious diseases and cancer difficult. Indeed, therapy resistance has become a key challenge for global health. Therefore, ideas of how to control evolving populations to overcome this threat are valuable. Here we use the mathematical concepts of stochastic optimal control to study what is needed to control evolving populations. Following established routes to calculate control ...[more]
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