Ontology highlight
ABSTRACT:
SUBMITTER: Furuhashi M
PROVIDER: S-EPMC4315049 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Furuhashi Masato M Saitoh Shigeyuki S Shimamoto Kazuaki K Miura Tetsuji T
Clinical Medicine Insights. Cardiology 20140101 Suppl 3
Over the past decade, evidences of an integration of metabolic and inflammatory pathways, referred to as metaflammation in several aspects of metabolic syndrome, have been accumulating. Fatty acid-binding protein 4 (FABP4), also known as adipocyte FABP (A-FABP) or aP2, is mainly expressed in adipocytes and macrophages and plays an important role in the development of insulin resistance and atherosclerosis in relation to metaflammation. Despite lack of a typical secretory signal peptide, FABP4 ha ...[more]