Ontology highlight
ABSTRACT:
SUBMITTER: Andersen KA
PROVIDER: S-EPMC4315656 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Protein science : a publication of the Protein Society 20150115 2
The post-translational modification of proteins with ubiquitin can take on many forms, including the decoration of substrates with polymeric ubiquitin chains. These chains are linked through one of the seven lysine residues in ubiquitin, with the potential to form a panoply of linkage combinations as the chain length increases. The ensuing structural diversity of modifications serves a variety of signaling functions. Still, some linkages are present at a much higher level than others in cellulo. ...[more]