Ontology highlight
ABSTRACT:
SUBMITTER: Wang L
PROVIDER: S-EPMC4316970 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Wang Lei L Liu Xiuheng X Chen Hui H Chen Zhiyuan Z Weng Xiaodong X Qiu Tao T Liu Lin L
Experimental and therapeutic medicine 20150120 3
Renal ischemia and reperfusion (I/R) injury, which commonly occurs in kidney transplantation, is the leading cause of acute kidney injury. Picroside II possesses a wide range of pharmacological effects, including anti-apoptosis effects. In the present study, the ability of picroside II to attenuate apoptosis in a rat model of renal I/R injury was investigated. Sprague-Dawley rats were subjected to 45 min of ischemia followed by 24 h of reperfusion. Prior to reperfusion, the rats were treated wit ...[more]