Unknown

Dataset Information

0

Medical prevention of breast cancer.

ABSTRACT: Breast cancer is the most common cancer of women in Western Europe and North America. Effective strategies of medical prevention could reduce the burden of breast cancer mortality. The best evidence for a risk reduction exists for hormonal agents such as tamoxifen and raloxifene (22-72%) or aromatase inhibitors (50-65%). However, the severity of side effects and the lack of evidence for an improved survival compromise the risk/benefit balance. In this review the results of chemoprevention studies, including new treatment approaches, are summarized with critical discussion of their use in clinical practice.

SUBMITTER: Stubert J 

PROVIDER: S-EPMC4317676 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Medical prevention of breast cancer.

Stubert Johannes J   Dieterich Max M   Gerber Bernd B  

Breast care (Basel, Switzerland) 20141201 6

Breast cancer is the most common cancer of women in Western Europe and North America. Effective strategies of medical prevention could reduce the burden of breast cancer mortality. The best evidence for a risk reduction exists for hormonal agents such as tamoxifen and raloxifene (22-72%) or aromatase inhibitors (50-65%). However, the severity of side effects and the lack of evidence for an improved survival compromise the risk/benefit balance. In this review the results of chemoprevention studie  ...[more]

Similar Datasets

Transcriptomics Breast cancer prevention with liquiritigenin
2023-08-30 | GSE223524 | GEO
Unknown Cardiovascular Prevention Strategies in Breast Cancer.
| S-EPMC8352277 | biostudies-literature
Transcriptomics Breast cancer prevention by short-term inhibition of TGFβ signaling
2022-11-02 | GSE184095 | GEO
Unknown Tamoxifen for prevention of breast cancer: extended long-term follow-up of the IBIS-I breast cancer prevention trial.
| S-EPMC4772450 | biostudies-literature
Unknown The genomic signature of breast cancer prevention.
| S-EPMC3978512 | biostudies-literature
Unknown Medications for Primary Prevention of Breast Cancer.
| S-EPMC8216042 | biostudies-literature
Unknown Celecoxib in breast cancer prevention and therapy.
| S-EPMC6208493 | biostudies-literature
Unknown Triple negative breast cancer: unmet medical needs.
| S-EPMC3244802 | biostudies-literature
Unknown Breast Cancer Prevention: Current Approaches and Future Directions.
| S-EPMC5939980 | biostudies-literature
Unknown Current strategies for the prevention of breast cancer.
| S-EPMC4018310 | biostudies-literature