Ontology highlight
ABSTRACT:
SUBMITTER: Estrella MM
PROVIDER: S-EPMC4318914 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Estrella Michelle M MM Li Man M Tin Adrienne A Abraham Alison G AG Shlipak Michael G MG Penugonda Sudhir S Hussain Shehnaz K SK Palella Frank J FJ Wolinsky Steven M SM Martinson Jeremy J JJ Parekh Rulan S RS Kao W H Linda WH
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20141003 4
<h4>Background</h4>Existing data suggest that human immunodeficiency virus (HIV)-infected African Americans carrying 2 copies of the APOL1 risk alleles have greater risk of kidney disease than noncarriers. We sought to determine whether HIV RNA suppression mitigates APOL1-related kidney function decline among African Americans enrolled in the Multicenter AIDS Cohort Study.<h4>Methods</h4>We genotyped HIV-infected men for the G1 and G2 risk alleles and ancestry informative markers. Mixed-effects ...[more]