Ontology highlight
ABSTRACT:
SUBMITTER: Baden LR
PROVIDER: S-EPMC4318919 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Baden Lindsey R LR Liu Jinyan J Li Hualin H Johnson Jennifer A JA Walsh Stephen R SR Kleinjan Jane A JA Engelson Brian A BA Peter Lauren L Abbink Peter P Milner Danny A DA Golden Kevin L KL Viani Kyle L KL Stachler Matthew D MD Chen Benjamin J BJ Pau Maria G MG Weijtens Mo M Carey Brittany R BR Miller Caroline A CA Swann Edith M EM Wolff Mark M Loblein Hayley H Seaman Michael S MS Dolin Raphael R Barouch Dan H DH
The Journal of infectious diseases 20140826 4
<h4>Background</h4>Defining mucosal immune responses and inflammation to candidate human immunodeficiency virus type 1 (HIV-1) vaccines represents a current research priority for the HIV-1 vaccine field. In particular, it is unclear whether intramuscular immunization can elicit immune responses at mucosal surfaces in humans.<h4>Methods</h4>In this double-blind, randomized, placebo-controlled clinical trial, we evaluated systemic and mucosal immune responses to a candidate adenovirus serotype 26 ...[more]