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An alkoxide-directed alkyne-allene cross-coupling for stereoselective synthesis of 1,4-dienes.

ABSTRACT: A titanium alkoxide-mediated convergent coupling between internal alkynes and allenes is described for the regio- and stereocontrolled synthesis of substituted acyclic 1,4-dienes.

SUBMITTER: Shimp HL

PROVIDER: S-EPMC4319186 | biostudies-literature | 2007 Nov

REPOSITORIES: biostudies-literature

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An alkoxide-directed alkyne-allene cross-coupling for stereoselective synthesis of 1,4-dienes.

Shimp Heidi L HL Micalizio Glenn C GC

Chemical communications (Cambridge, England) 20070823 43

A titanium alkoxide-mediated convergent coupling between internal alkynes and allenes is described for the regio- and stereocontrolled synthesis of substituted acyclic 1,4-dienes. ...[more]

PMID: 17971979

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