Smart polymeric nanoparticles for cancer gene delivery.
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ABSTRACT:
SUBMITTER: Lin G
PROVIDER: S-EPMC4319689 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Publications
Smart polymeric nanoparticles for cancer gene delivery.
Lin Guimei G Zhang Hong H Huang Leaf L
Molecular pharmaceutics 20150107 2
The massive amount of human genetic information already available has accelerated the identification of target genes, making gene and nucleic acid therapy the next generation of medicine. Nanoparticle (NP)-based anticancer gene therapy treatment has received significant interest in this evolving field. Recent advances in vector technology have improved gene transfection efficiencies of nonviral vectors to a level similar to viruses. This review serves as an introduction to surface modifications ...[more]
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