Ontology highlight
ABSTRACT:
SUBMITTER: Ding Y
PROVIDER: S-EPMC4319740 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
PloS one 20150206 2
Consumption of Pu-erh has been reported to result in numerous health benefits, but the mechanisms underlying purported weight-loss and lowering of lipid are poorly understood. Here, we used the nematode Caenorhaditis elegans to explore the water extract of Pu-erh tea (PTE) functions to reduce fat storage. We found that PTE down-regulates the expression of the master fat regulator SBP-1, a homologue of sterol regulatory element binding protein (SREBP) and its target stearoyl-CoA desaturase (SCD), ...[more]