Ontology highlight
ABSTRACT:
SUBMITTER: Tantravahi SK
PROVIDER: S-EPMC4320862 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Tantravahi Srinivas K SK Albertson Daniel D Agarwal Archana M AM Ravulapati Sowmya S Poole Austin A Patel Shiven B SB Hawatmeh Jamil S JS Straubhar Alli M AM Liu Ting T Stenehjem David D DD Agarwal Neeraj N
Journal of oncology 20150120
Metastatic renal cell carcinoma with sarcomatoid histology (SmRCC) is associated with poor survival. No data is available from randomized trials on the efficacy of vascular endothelial growth factor (VEGF) and mammalian target of rapamycin (mTOR) inhibitors in SmRCC. We identified SmRCC patients from a single institutional database. To identify predictive and prognostic biomarkers, immunohistochemistry (IHC) analysis was performed on the tumor samples for downstream targets of VEGF and mTOR path ...[more]