Ontology highlight
ABSTRACT:
SUBMITTER: Brand MD
PROVIDER: S-EPMC4321783 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Brand M D MD Orr A L AL Perevoshchikova I V IV Quinlan C L CL
The British journal of dermatology 20130701
Mitochondria constitute an important topic of biomedical enquiry (one paper in every 154 indexed in PubMed since 1998 is retrieved by the keyword 'mitochondria') because of widespread recognition of their importance in cell physiology and pathology. Mitochondrial dysfunction is widely implicated in ageing and in the diseases of ageing, through dysfunction in adenosine triphosphate (ATP) synthesis, Ca(2+) homeostasis, central metabolic pathways or radical production. Nonetheless, the mechanisms a ...[more]