Racial differences in CT phenotypes in COPD.
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ABSTRACT:
SUBMITTER: Hansel NN
PROVIDER: S-EPMC4321889 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Publications
Racial differences in CT phenotypes in COPD.
Hansel Nadia N NN Washko George R GR Foreman Marilyn G MG Han MeiLan K MK Hoffman Eric A EA DeMeo Dawn L DL Barr R Graham RG Van Beek Edwin J R EJ Kazerooni Ella A EA Wise Robert A RA Brown Robert H RH Black-Shinn Jennifer J Hokanson John E JE Hanania Nicola A NA Make Barry B Silverman Edwin K EK Crapo James D JD Dransfield Mark T MT
COPD 20130201 1
<h4>Background</h4>Whether African Americans (AA) are more susceptible to COPD than non-Hispanic Whites (NHW) and whether racial differences in disease phenotype exist is controversial. The objective is to determine racial differences in the extent of emphysema and airway remodeling in COPD.<h4>Methods</h4>First, 2,500 subjects enrolled in the COPDGene study were used to evaluate racial differences in quantitative CT (QCT) parameters of% emphysema, air trapping and airway wall thickness. Indepen ...[more]
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