The Serum Immunoglobulin G Glycosylation Signature of Gastric Cancer.
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ABSTRACT:
SUBMITTER: Ruhaak LR
PROVIDER: S-EPMC4322429 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Publications
The Serum Immunoglobulin G Glycosylation Signature of Gastric Cancer.
Ruhaak L Renee LR Barkauskas Donald A DA Torres Javier J Cooke Cara L CL Wu Lauren D LD Stroble Carol C Ozcan Sureyya S Williams Cynthia C CC Camorlinga Margarita M Rocke David M DM Lebrilla Carlito B CB Solnick Jay V JV
EuPA open proteomics 20150301
Biomarkers may facilitate detection of gastric cancer at an earlier stage and reduce mortality. Here we sought to determine if the glycosylation profile of serum immunoglobulin G (IgG) could distinguish patients with non-atrophic gastritis (NAG), duodenal ulcer (DU) and gastric cancer (GC). Serum IgG was released and analyzed using nano-LC-TOF mass spectrometry. Statistically significant false discovery rate (FDR)-adjusted p-values were observed for 18 glycans, eight that differed significantly ...[more]
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2019-01-24 | PXD010911 | Pride