Unknown

Dataset Information

0

Exosomes: novel biomarkers for clinical diagnosis.


ABSTRACT: Exosomes are 30-120 nm endocytic membrane-derived vesicles that participate in cell-to-cell communication and protein and RNA delivery. Exosomes harbor a variety of proteins, nucleic acids, and lipids and are present in many and perhaps all bodily fluids. A significant body of literature has demonstrated that molecular constituents of exosomes, especially exosomal proteins and microRNAs (miRNAs), hold great promise as novel biomarkers for clinical diagnosis. In this minireview, we summarize recent advances in the research of exosomal biomarkers and their potential application in clinical diagnostics. We also provide a brief overview of the formation, function, and isolation of exosomes.

SUBMITTER: Lin J 

PROVIDER: S-EPMC4322857 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

altmetric image

Publications

Exosomes: novel biomarkers for clinical diagnosis.

Lin Jin J   Li Jing J   Huang Bo B   Liu Jing J   Chen Xin X   Chen Xi-Min XM   Xu Yan-Mei YM   Huang Lin-Feng LF   Wang Xiao-Zhong XZ  

TheScientificWorldJournal 20150127


Exosomes are 30-120 nm endocytic membrane-derived vesicles that participate in cell-to-cell communication and protein and RNA delivery. Exosomes harbor a variety of proteins, nucleic acids, and lipids and are present in many and perhaps all bodily fluids. A significant body of literature has demonstrated that molecular constituents of exosomes, especially exosomal proteins and microRNAs (miRNAs), hold great promise as novel biomarkers for clinical diagnosis. In this minireview, we summarize rece  ...[more]

Similar Datasets

| S-EPMC9530625 | biostudies-literature
| S-EPMC7400738 | biostudies-literature
| S-EPMC7441435 | biostudies-literature
| S-EPMC3422911 | biostudies-literature
| S-EPMC3255362 | biostudies-literature
| S-EPMC10901968 | biostudies-literature
| S-EPMC6760223 | biostudies-literature
| S-EPMC9720984 | biostudies-literature
| S-EPMC3876995 | biostudies-literature
| S-EPMC7921467 | biostudies-literature