Quantitative bacterial transcriptomics with RNA-seq.
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ABSTRACT:
SUBMITTER: Creecy JP
PROVIDER: S-EPMC4323862 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Publications
Quantitative bacterial transcriptomics with RNA-seq.
Creecy James P JP Conway Tyrrell T
Current opinion in microbiology 20141205
RNA sequencing has emerged as the premier approach to study bacterial transcriptomes. While the earliest published studies analyzed the data qualitatively, the data are readily digitized and lend themselves to quantitative analysis. High-resolution RNA sequence (RNA-seq) data allows transcriptional features (promoters, terminators, operons, among others) to be pinpointed on any bacterial transcriptome. Once the transcriptome is mapped, the activity of transcriptional features can be quantified. ...[more]
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