Ontology highlight
ABSTRACT:
SUBMITTER: Unissa AN
PROVIDER: S-EPMC4324114 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Unissa A Nusrath AN Selvakumar N N Narayanan Sujatha S Suganthi C C Hanna L E LE
BioMed research international 20150128
Mutation at codon 315 of katG gene is the major cause for isoniazid (INH) resistance in Mycobacterium tuberculosis (M. tuberculosis). Substitution at codon 315 of katG gene was analyzed in 85 phenotypically resistant isolates collected from various parts of southern India by direct sequencing method. The obtained results were interpreted in the context of minimum inhibitory concentration (MIC) of INH. Of the 85 phenotypically resistant isolates, 56 (66%) were also correlated by the presence of r ...[more]