Ontology highlight
ABSTRACT:
SUBMITTER: Shiimura Y
PROVIDER: S-EPMC4324914 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Shiimura Yuki Y Ohgusu Hideko H Sato Takahiro T Kojima Masayasu M
International journal of endocrinology 20150128
To examine the gene expression of ghrelin, a growth hormone releasing and appetite stimulating hormone from stomach, we constructed human ghrelin promoter-reporter vectors and analyzed the promoter activity. The ghrelin promoter activity was high when cultured cells that express ghrelin mRNA endogenously like TT or ECC10 cells were used, indicating that these cells contain factors necessary for full expression of the human ghrelin gene. The human ghrelin promoter contains both positive and negat ...[more]