Ontology highlight
ABSTRACT:
SUBMITTER: Della Torre M
PROVIDER: S-EPMC4326076 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Della Torre Micaela M Hibbard Judith U JU Jeong Hyunyoung H Fischer James H JH
American journal of obstetrics and gynecology 20100901 3
<h4>Objective</h4>The goals of the study were to estimate the pharmacokinetic parameters of standard dose betamethasone in a large obstetrics population and evaluate the effect of maternal body size and multiple gestation on the pharmacokinetic parameters and their observed variability.<h4>Study design</h4>This was a prospective pharmacokinetic study. Liquid chromatography mass spectrometry was used to measure betamethasone plasma concentrations. Pharmacokinetic parameters and significant clinic ...[more]