Ontology highlight
ABSTRACT:
SUBMITTER: Luke JJ
PROVIDER: S-EPMC4326637 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Luke Jason J JJ Triozzi Pierre L PL McKenna Kyle C KC Van Meir Erwin G EG Gershenwald Jeffrey E JE Bastian Boris C BC Gutkind J Silvio JS Bowcock Anne M AM Streicher Howard Z HZ Patel Poulam M PM Sato Takami T Sossman Jeffery A JA Sznol Mario M Welch Jack J Thurin Magdalena M Selig Sara S Flaherty Keith T KT Carvajal Richard D RD
Pigment cell & melanoma research 20140901 2
Uveal melanoma is the most common intraocular malignancy although it is a rare subset of all melanomas. Uveal melanoma has distinct biology relative to cutaneous melanoma, with widely divergent patient outcomes. Patients diagnosed with a primary uveal melanoma can be stratified for risk of metastasis by cytogenetics or gene expression profiling, with approximately half of patients developing metastatic disease, predominately hepatic in location, over a 15-yr period. Historically, no systemic the ...[more]