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Microencapsulation of indocyanine green for potential applications in image-guided drug delivery.


ABSTRACT: We present a novel process to encapsulate indocyanine green (ICG) in liposomal droplets at high concentration for potential applications in image-guided drug delivery. The microencapsulation process follows two consecutive steps of droplet formation by liquid-driven coaxial flow focusing (LDCFF) and solvent removal by oil phase dewetting. These biocompatible lipid vesicles may have important applications in drug delivery and fluorescence imaging.

SUBMITTER: Zhu Z 

PROVIDER: S-EPMC4332816 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature

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Microencapsulation of indocyanine green for potential applications in image-guided drug delivery.

Zhu Zhiqiang Z   Si Ting T   Xu Ronald X RX  

Lab on a chip 20150201 3


We present a novel process to encapsulate indocyanine green (ICG) in liposomal droplets at high concentration for potential applications in image-guided drug delivery. The microencapsulation process follows two consecutive steps of droplet formation by liquid-driven coaxial flow focusing (LDCFF) and solvent removal by oil phase dewetting. These biocompatible lipid vesicles may have important applications in drug delivery and fluorescence imaging. ...[more]

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