Ontology highlight
ABSTRACT:
SUBMITTER: Erkizan HV
PROVIDER: S-EPMC4333382 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Erkizan Hayriye Verda HV Schneider Jeffrey A JA Sajwan Kamal K Graham Garrett T GT Griffin Brittany B Chasovskikh Sergey S Youbi Sarah E SE Kallarakal Abraham A Chruszcz Maksymilian M Padmanabhan Radhakrishnan R Casey John L JL Üren Aykut A Toretsky Jeffrey A JA
Nucleic acids research 20150106 2
RNA helicases impact RNA structure and metabolism from transcription through translation, in part through protein interactions with transcription factors. However, there is limited knowledge on the role of transcription factor influence upon helicase activity. RNA helicase A (RHA) is a DExH-box RNA helicase that plays multiple roles in cellular biology, some functions requiring its activity as a helicase while others as a protein scaffold. The oncogenic transcription factor EWS-FLI1 requires RHA ...[more]