Ontology highlight
ABSTRACT:
SUBMITTER: Somani G
PROVIDER: S-EPMC4333625 | biostudies-literature | 2015 Jan-Mar
REPOSITORIES: biostudies-literature
Somani Gauresh G Kulkarni Chinmay C Shinde Prashant P Shelke Rupesh R Laddha Kirti K Sathaye Sadhana S
Journal of pharmacy & bioallied sciences 20150101 1
<h4>Introduction</h4>Alzheimer's disease (AD) has increased at an alarming rate and is now a worldwide health problem. Inhibitors of acetylcholinesterase (AChE) leading to inhibition of acetylcholine breakdown constitute the main therapeutic strategy for AD. Psoralen was investigated as inhibitor of AChE enzyme in an attempt to explore its potential for the management of AD.<h4>Materials and methods</h4>Psoralen was isolated from powdered Psoralea corylifolia fruits. AChE enzyme inhibitory activ ...[more]