Ontology highlight
ABSTRACT:
SUBMITTER: Zaki N
PROVIDER: S-EPMC4334629 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Zaki Nazar N Mohamed Elfadil A EA Mora Antonio A
Biochemistry research international 20150204
The identification and characterization of protein complexes implicated in protein-protein interaction data are crucial to the understanding of the molecular events under normal and abnormal physiological conditions. This paper provides a novel characterization of subcomplexes in protein interaction databases, stressing definition and representation issues, quantification, biological validation, network metrics, motifs, modularity, and gene ontology (GO) terms. The paper introduces the concept o ...[more]