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Sleep deprivation and time-on-task performance decrement in the rat psychomotor vigilance task.


ABSTRACT:

Study objectives

The rat psychomotor vigilance task (rPVT) was developed as a rodent analog of the human psychomotor vigilance task (hPVT). We examined whether rPVT performance displays time-on-task effects similar to those observed on the hPVT.

Design

The rPVT requires rats to respond to a randomly presented light stimulus to obtain a water reward. Rats were water deprived for 22 h prior to each 30-min rPVT session to motivate performance. We analyzed rPVT performance over time on task and as a function of the response-stimulus interval, at baseline and after sleep deprivation.

Setting

The study was conducted in an academic research vivarium.

Participants

Male Long-Evans rats were trained to respond to a 0.5 sec stimulus light within 3 sec of stimulus onset. Complete data were available for n = 20 rats.

Interventions

Rats performed the rPVT for 30 min at baseline and after 24 h total sleep deprivation by gentle handling.

Measurements and results

Compared to baseline, sleep deprived rats displayed increased performance lapses and premature responses, similar to hPVT lapses of attention and false starts. However, in contrast to hPVT performance, the time-on-task performance decrement was not significantly enhanced by sleep deprivation. Moreover, following sleep deprivation, rPVT response times were not consistently increased after short response-stimulus intervals.

Conclusions

The rPVT manifests similarities to the hPVT in global performance outcomes, but not in post-sleep deprivation effects of time on task and response-stimulus interval.

SUBMITTER: Oonk M 

PROVIDER: S-EPMC4335522 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature

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Publications

Sleep deprivation and time-on-task performance decrement in the rat psychomotor vigilance task.

Oonk Marcella M   Davis Christopher J CJ   Krueger James M JM   Wisor Jonathan P JP   Van Dongen Hans P A HP  

Sleep 20150301 3


<h4>Study objectives</h4>The rat psychomotor vigilance task (rPVT) was developed as a rodent analog of the human psychomotor vigilance task (hPVT). We examined whether rPVT performance displays time-on-task effects similar to those observed on the hPVT.<h4>Design</h4>The rPVT requires rats to respond to a randomly presented light stimulus to obtain a water reward. Rats were water deprived for 22 h prior to each 30-min rPVT session to motivate performance. We analyzed rPVT performance over time o  ...[more]

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