Genetic susceptibility and pulmonary fibrosis.
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ABSTRACT:
SUBMITTER: Mathai SK
PROVIDER: S-EPMC4337021 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Publications
Genetic susceptibility and pulmonary fibrosis.
Mathai Susan K SK Schwartz David A DA Warg Laura A LA
Current opinion in pulmonary medicine 20140901 5
<h4>Purpose of review</h4>Recent genetic findings have identified new targets of investigation in the field of pulmonary fibrosis and have the potential to change clinical care.<h4>Recent findings</h4>These findings implicate alterations in host defense, cell-to-cell adhesion, and aging and senescence in the pathophysiology of pulmonary fibrosis. At least one common genetic variant strongly associated with pulmonary fibrosis appears to have prognostic implications for patients.<h4>Summary</h4>Th ...[more]
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