Ontology highlight
ABSTRACT:
SUBMITTER: Deiteren A
PROVIDER: S-EPMC4337694 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Deiteren A A De Man J G JG Pelckmans P A PA De Winter B Y BY
British journal of pharmacology 20150112 5
Histamine is a well-established mediator involved in a variety of physiological and pathophysiological mechanisms and exerts its effect through activation of four histamine receptors (H1-H₄). The histamine H₄ receptor is the newest member of this histamine receptor family, and is expressed throughout the gastrointestinal tract as well as in the liver, pancreas and bile ducts. Functional studies using a combination of selective and non-selective H₄ receptor ligands have rapidly increased our know ...[more]