Ontology highlight
ABSTRACT:
SUBMITTER: Venugopala KN
PROVIDER: S-EPMC4338777 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Venugopala Katharigatta N KN Govender Reshme R Khedr Mohammed A MA Khedr Mohammed A MA Venugopala Rashmi R Aldhubiab Bandar E BE Harsha Sree S Odhav Bharti B
Drug design, development and therapy 20150217
Dihydropyrimidine scaffold has a wide range of potential pharmacological activities such as antiviral, antitubercular, antimalarial, anti-inflammatory, and anticancer properties. 5-Lipoxygenase enzyme is an enzyme responsible for the metabolism of arachidonic acid to leukotrienes. The elevated levels of this enzyme and its metabolites in cancer cells have a direct relation on the development of cancer when compared to normal cells. The development of novel lipoxygenase inhibitors can have a majo ...[more]