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An update on current management of advanced renal cell cancer, biomarkers, and future directions.

ABSTRACT: In the past decade, metastatic renal cell carcinoma (mRCC) treatment underwent significant advancement that resulted in an unprecedented improvement in the prognosis of this disease. This review will provide an updated review of currently approved treatment options, namely antiangiogenic and immunotherapy, as well as treatment guideline recommended by the National Comprehensive Cancer Network (NCCN). We will summarize studies ongoing in determining prognostic and predictive biomarkers in maximizing therapeutic benefit in the treatment of this disease. Lastly, we will discuss promising agents in clinical testing.

SUBMITTER: Zhi WI

PROVIDER: S-EPMC4339053 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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An update on current management of advanced renal cell cancer, biomarkers, and future directions.

Zhi Wanqing Iris WI Kim Jenny J JJ

Annals of cancer research 20140101 2

In the past decade, metastatic renal cell carcinoma (mRCC) treatment underwent significant advancement that resulted in an unprecedented improvement in the prognosis of this disease. This review will provide an updated review of currently approved treatment options, namely antiangiogenic and immunotherapy, as well as treatment guideline recommended by the National Comprehensive Cancer Network (NCCN). We will summarize studies ongoing in determining prognostic and predictive biomarkers in maximiz ...[more]

PMID: 25722991

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