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Systems biology of polycystic kidney disease: a critical review.


ABSTRACT: The proliferation and diminishing costs of 'omics' approaches have finally opened the doors for small and medium laboratories to enter the 'systems biology era'. This is a welcome evolution that requires a new framework to design, interpret, and validate studies. Here, we highlight some of the challenges, contributions, and prospects of the 'cyst-ems biology' of polycystic kidney disease.

SUBMITTER: Menezes LF 

PROVIDER: S-EPMC4339620 | biostudies-literature | 2015 Jan-Feb

REPOSITORIES: biostudies-literature

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Systems biology of polycystic kidney disease: a critical review.

Menezes Luis Fernando LF   Germino Gregory G GG  

Wiley interdisciplinary reviews. Systems biology and medicine 20150101 1


The proliferation and diminishing costs of 'omics' approaches have finally opened the doors for small and medium laboratories to enter the 'systems biology era'. This is a welcome evolution that requires a new framework to design, interpret, and validate studies. Here, we highlight some of the challenges, contributions, and prospects of the 'cyst-ems biology' of polycystic kidney disease. ...[more]

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