Ontology highlight
ABSTRACT:
SUBMITTER: Grant RC
PROVIDER: S-EPMC4339623 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Grant Robert C RC Selander Iris I Connor Ashton A AA Selvarajah Shamini S Borgida Ayelet A Briollais Laurent L Petersen Gloria M GM Lerner-Ellis Jordan J Holter Spring S Gallinger Steven S
Gastroenterology 20141202 3
<h4>Background & aims</h4>We investigated the prevalence of germline mutations in APC, ATM, BRCA1, BRCA2, CDKN2A, MLH1, MSH2, MSH6, PALB2, PMS2, PRSS1, STK11, and TP53 in patients with pancreatic cancer.<h4>Methods</h4>The Ontario Pancreas Cancer Study enrolls consenting participants with pancreatic cancer from a province-wide electronic pathology database; 708 probands were enrolled from April 2003 through August 2012. To improve the precision of BRCA2 prevalence estimates, 290 probands were se ...[more]