Ontology highlight
ABSTRACT:
SUBMITTER: Ikram NK
PROVIDER: S-EPMC4340357 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Journal of chemical information and modeling 20150129 2
Recent outbreaks of highly pathogenic and occasional drug-resistant influenza strains have highlighted the need to develop novel anti-influenza therapeutics. Here, we report computational and experimental efforts to identify influenza neuraminidase inhibitors from among the 3000 natural compounds in the Malaysian-Plants Natural-Product (NADI) database. These 3000 compounds were first docked into the neuraminidase active site. The five plants with the largest number of top predicted ligands were ...[more]