Ontology highlight
ABSTRACT:
SUBMITTER: Kirkham GR
PROVIDER: S-EPMC4341216 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Kirkham Glen R GR Britchford Emily E Upton Thomas T Ware James J Gibson Graham M GM Devaud Yannick Y Ehrbar Martin M Padgett Miles M Allen Stephanie S Buttery Lee D LD Shakesheff Kevin K
Scientific reports 20150226
The accurate study of cellular microenvironments is limited by the lack of technologies that can manipulate cells in 3D at a sufficiently small length scale. The ability to build and manipulate multicellular microscopic structures will facilitate a more detailed understanding of cellular function in fields such as developmental and stem cell biology. We present a holographic optical tweezers based technology to accurately generate bespoke cellular micro-architectures. Using embryonic stem cells, ...[more]