Ontology highlight
ABSTRACT:
SUBMITTER: Hayakawa S
PROVIDER: S-EPMC4341480 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Hayakawa Satoko S Ohashi Koji K Shibata Rei R Kataoka Yoshiyuki Y Miyabe Megumi M Enomoto Takashi T Joki Yusuke Y Shimizu Yuuki Y Kambara Takahiro T Uemura Yusuke Y Yuasa Daisuke D Ogawa Hayato H Matsuo Kazuhiro K Hiramatsu-Ito Mizuho M van den Hoff Maurice J B MJ Walsh Kenneth K Murohara Toyoaki T Ouchi Noriyuki N
Journal of the American Society of Nephrology : JASN 20140728 3
Heart disease contributes to the progression of CKD. Heart tissue produces a number of secreted proteins, also known as cardiokines, which participate in intercellular and intertissue communication. We recently reported that follistatin-like 1 (Fstl1) functions as a cardiokine with cardioprotective properties. Here, we investigated the role of cardiac Fstl1 in renal injury after subtotal nephrectomy. Cardiac-specific Fstl1-deficient (cFstl1-KO) mice and wild-type mice were subjected to subtotal ...[more]