Ontology highlight
ABSTRACT:
SUBMITTER: Marrazzo JM
PROVIDER: S-EPMC4341965 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Marrazzo Jeanne M JM Ramjee Gita G Richardson Barbra A BA Gomez Kailazarid K Mgodi Nyaradzo N Nair Gonasagrie G Palanee Thesla T Nakabiito Clemensia C van der Straten Ariane A Noguchi Lisa L Hendrix Craig W CW Dai James Y JY Ganesh Shayhana S Mkhize Baningi B Taljaard Marthinette M Parikh Urvi M UM Piper Jeanna J Mâsse Benoît B Grossman Cynthia C Rooney James J Schwartz Jill L JL Watts Heather H Marzinke Mark A MA Hillier Sharon L SL McGowan Ian M IM Chirenje Z Mike ZM
The New England journal of medicine 20150201 6
<h4>Background</h4>Reproductive-age women need effective interventions to prevent the acquisition of human immunodeficiency virus type 1 (HIV-1) infection.<h4>Methods</h4>We conducted a randomized, placebo-controlled trial to assess daily treatment with oral tenofovir disoproxil fumarate (TDF), oral tenofovir-emtricitabine (TDF-FTC), or 1% tenofovir (TFV) vaginal gel as preexposure prophylaxis against HIV-1 infection in women in South Africa, Uganda, and Zimbabwe. HIV-1 testing was performed mon ...[more]