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Plasmonics-enhanced and optically modulated delivery of gold nanostars into brain tumor.


ABSTRACT: Plasmonics-active gold nanostars exhibiting strong imaging contrast and efficient photothermal transduction were synthesized for a novel pulsed laser-modulated plasmonics-enhanced brain tumor microvascular permeabilization. We demonstrate a selective, optically modulated delivery of nanoprobes into the tumor parenchyma with minimal off-target distribution.

SUBMITTER: Yuan H 

PROVIDER: S-EPMC4343032 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature

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Plasmonics-active gold nanostars exhibiting strong imaging contrast and efficient photothermal transduction were synthesized for a novel pulsed laser-modulated plasmonics-enhanced brain tumor microvascular permeabilization. We demonstrate a selective, optically modulated delivery of nanoprobes into the tumor parenchyma with minimal off-target distribution. ...[more]

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