Noninvasive test for tuberculosis detection among primates.
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ABSTRACT:
SUBMITTER: Wolf TM
PROVIDER: S-EPMC4344255 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Publications
Noninvasive test for tuberculosis detection among primates.
Wolf Tiffany M TM Mugisha Lawrence L Shoyama Fernanda Miyagaki FM O'Malley Melanie J MJ Flynn JoAnne L JL Asiimwe Benon B Travis Dominic A DA Singer Randall S RS Sreevatsan Srinand S
Emerging infectious diseases 20150301 3
Traditional testing methods have limited epidemiologic studies of tuberculosis among free-living primates. PCR amplification of insertion element IS6110 of Mycobacterium tuberculosis from fecal samples was evaluated as a noninvasive screening test for tuberculosis in primates. Active tuberculosis was detected among inoculated macaques and naturally exposed chimpanzees, demonstrating the utility of this test. ...[more]
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