Association of polyphenols from oranges and apples with specific intestinal microorganisms in systemic lupus erythematosus patients.

ABSTRACT: Our group has recently shown the existence of a gut microbial dysbiosis in systemic lupus erythematosus (SLE), supporting previous evidence involving intestinal bacteria in the initiation and amplification of autoimmune diseases. While several studies have addressed the use of dietary fibres to modify intestinal microbiota, information about other correlated components, such as polyphenols, is scarce. The aim of this work was to identify dietary components able to influence this altered microbiota in 20 SLE women and 20 age-matched controls. Food intake was recorded by means of a food frequency questionnaire. The intake of fibres was calculated from Marlett tables, and Phenol-Explorer was used for polyphenol consumption. Results showed positive associations between flavone intake and Blaut

SUBMITTER: Cuervo A 

PROVIDER: S-EPMC4344589 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature