Ontology highlight
ABSTRACT:
SUBMITTER: Lei F
PROVIDER: S-EPMC4344598 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Lei Feng F Gao Du D Zhang Xi X Xu Jun J Xu Min-Juan MJ
Marine drugs 20150128 2
Xiamenmycin A is an antifibrotic leading compound with a benzopyran skeleton that is isolated from mangrove-derived Streptomyces xiamenensis. As a promising small molecule for fibrotic diseases, less information is known about its metabolic characteristics in vivo. In this study, the time-course of xiamenmycin A in mouse plasma was investigated by relative quantification. After two types of administration of xiamenmycin A at a single dose of 10 mg/kg, the plasma concentrations were measured quan ...[more]