Decreased Resting-State Connectivity between Neurocognitive Networks in Treatment Resistant Depression.
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ABSTRACT:
SUBMITTER: de Kwaasteniet BP
PROVIDER: S-EPMC4345766 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Decreased Resting-State Connectivity between Neurocognitive Networks in Treatment Resistant Depression.
de Kwaasteniet Bart P BP Rive Maria M MM Ruhé Henricus G HG Schene Aart H AH Veltman Dick J DJ Fellinger Lisanne L van Wingen Guido A GA Denys Damiaan D
Frontiers in psychiatry 20150302
Approximately one-third of patients with major depressive disorder (MDD) do not achieve remission after various treatment options and develop treatment resistant depression (TRD). So far, little is known about the pathophysiology of TRD. Studies in MDD patients showed aberrant functional connectivity (FC) of three "core" neurocognitive networks: the salience network (SN), cognitive control network (CCN), and default mode network (DMN). We used a cross-sectional design and performed resting-state ...[more]
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