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Isolation and characterization of Mayaro virus from a human in Acre, Brazil.

ABSTRACT: Mayaro virus (MAYV) is widely distributed throughout South America and is the etiologic agent of Mayaro fever, an acute febrile illness often presenting with arthralgic manifestations. The true incidence of MAYV infection is likely grossly underestimated because the symptomatic presentation is very similar to that of dengue fever and other acute febrile tropical diseases. We report the complete genome sequence of a MAYV isolate detected from an Acrelândia patient presenting with fever, chills, and sweating, but with no arthralgia. Results show that this isolate belongs to genotype D and is closely related to Bolivian strains. Our results suggest that the Acre/Mayaro strain is closely related to the progenitor of these Bolivian strains that were isolated between 2002 and 2006.

SUBMITTER: Terzian AC

PROVIDER: S-EPMC4347347 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature

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Isolation and characterization of Mayaro virus from a human in Acre, Brazil.

Terzian Ana Carolina B AC Auguste Albert J AJ Vedovello Danila D Ferreira Marcelo U MU da Silva-Nunes Mônica M Sperança Márcia A MA Suzuki Rodrigo B RB Juncansen Camila C Araújo João P JP Weaver Scott C SC Nogueira Maurício L ML

The American journal of tropical medicine and hygiene 20141215 2

Mayaro virus (MAYV) is widely distributed throughout South America and is the etiologic agent of Mayaro fever, an acute febrile illness often presenting with arthralgic manifestations. The true incidence of MAYV infection is likely grossly underestimated because the symptomatic presentation is very similar to that of dengue fever and other acute febrile tropical diseases. We report the complete genome sequence of a MAYV isolate detected from an Acrelândia patient presenting with fever, chills, a ...[more]

PMID: 25510721

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